Genomic Precision

 A SeraCare blog focused on precision medicine and advanced clinical diagnostics

Get Out of QC Spreadsheet Agony

iQ™ NGS QC Management software for easy assessment of assay performance

Posted by Dale Yuzuki on Jun 29, 2017 10:00:00 AM

As a manager of a clinical genomics laboratory, how many times have you been faced with the following situations?

  • You need to produce trending performance data over the past three months as a part of an internal audit
  • You need to examine the last runs performed that used a particular piece of equipment that you suspect may be out of specification
  • You need to produce a QC report for an upcoming regulatory inspection
  • You need to find out root cause of an assay failure

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Do you look forward to sifting through multiple spreadsheet files often stored in different network locations, or pestering your IT staff to write a custom SQL query to pull the required data from your in-house LIMS, or going back to your overflowing filing cabinet to collect the data across the runs in question?

SeraCare has developed a tool to support the entire NGS workflow from a QC perspective, with the flexibility to easily track many variables and metrics across the entire workflow from sample preparation through variant calling. The iQ NGS QC Management software enables variables such as reagent lots, operator shifts, and instrumentation to be imported into the software automatically using a Connector API. You can then easily review and assess run performance.

For Dr. Francine Blumental de Abreu, Assistant Director at the Laboratory for Clinical Genomics and Advanced Technology (CGAT) of Dartmouth-Hitchcock Medical Center, the iQ NGS QC Management software “has allowed us to track multiple QC metrics for each run, giving us new insights into how our assay is performing, and a higher level of confidence. It also makes it easy to demonstrate compliance and has reduced our audit preparation time. Our technologists are no longer spending hours manually tracking metrics on spreadsheets, and all the data we need to troubleshoot our assay is right at our fingertips.”

Hear Dr. de Abreu talk about the iQ NGS QC Management for yourself; her presentation at the Association for Molecular Pathology meeting is available online here as a video, or you can read a summary here as a PDF.

Automate the QC Data Analysis of Your Clinical NGS Test


Topics: NGS Management Software, QC Reporting