Genomic Precision

 A SeraCare blog focused on precision medicine and advanced clinical diagnostics

Tips for Better EGFR Mutation Testing

Posted by Catherine Huang on Jan 10, 2019 11:30:00 AM

Tips for Better EGFR Mutation Testing

Molecular testing of genomic alterations in the EGFR gene is critical to personalized treatment decisions for patients with advanced non-small cell lung cancer (NSCLC). However, the testing landscape is complex. Some mutations confer sensitivity, and others confer resistance to anti-EGFR targeted therapies.

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Topics: ctDNA, SeraSeq, Ffpe, EGFR

Video: What are the sources of variability in FFPE material?

Interview with Dr. Greg Tsongalis, Professor of Pathology, Dartmouth-Hitchcock Medical Center

Posted by Dale Yuzuki on Oct 27, 2015 11:16:00 AM

In this video interview Dr. Greg Tsongalis addresses sources of pre-analytic variability when processing formalin-fixed, paraffin-embedded (FFPE) samples in a pathology laboratory setting. By 'pre-analytic', he refers to the kinds of kits used for DNA extraction, and other factors that may have a significant impact on the quality of the results. He also discusses his work on clinical assay development for somatic mutation detection using NGS technology.

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Topics: Cancer, Pre-analytical, NGS, Variation, Mutation, Ffpe

 
 
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