Genomic Precision

 A SeraCare blog focused on precision medicine and advanced clinical diagnostics

Presenting NTRK Reference Materials for Global Assay Standardization at AACR 2019

Posted by Catherine Huang on Apr 8, 2019 3:00:00 PM

On the last morning of AACR 2019, I had the privilege of presenting a poster together with my colleague, Sebastian Bender from Bayer AG, in Berlin. Because of this, I didn’t have a chance to attend any talks, but I still wanted to finish out my blog series with highlights from each day of the conference.

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Topics: SeraSeq, AACR, NTRK, RNA fusion

NTRK Fusion Testing for New Therapies

Detecting & Managing Rare Pediatric & Adult Cancers

Posted by Omo Clement, Ph.D. on Feb 6, 2019 9:15:00 AM

Neurotrophic tyrosine receptor kinases (NTRK) can become abnormally fused to other genes resulting in growth signals that can lead to cancer in many organs of the human body. TRK gene fusion-based cancers are rare but present in pediatric and adult cancers such as lung, thyroid, colon, etc. (see, e.g., Figure 1).

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Topics: cancer, NTRK, RNA fusion