Accuracy of NGS results is extremely critical for clinical genomic laboratories, when developing, validating or running an assay. At the 2017 Precision Medicine World Conference a panel discussion entitled ‘Achieving Accurate NGS Test Results’ featured Dr. Greg Tsongalis, Director of Clinical Genomics and Advanced Technology at Dartmouth Hitchcock Medical Center; Dr. Dara Aisner, Associate Professor of Pathology at University of Colorado Anschutz Medical Campus School of Medicine; and Dr. Russell Garlick,
Chief Scientific Officer of SeraCare Life Sciences.
The individual presentations and ensuing discussion have been edited for clarity and summarized in a document called “Achieving High Levels of Accuracy from Next-Generation Sequencing Assays in Clinical Laboratories." This document lays out:
- The procedural steps that may introduce variability
- Key endpoints to focus on to mitigate that variability
- The importance of proper validation and execution of data analysis and data curation
- The benefits of inter-laboratory and cross-platform validation
Access the 2017 Precision Medicine World Conference document, “Achieving High Levels of Accuracy from Next-Generation Sequencing Assays in Clinical Laboratories” by clicking here.